Bills vs Panthers prediction

No Bills vs Panthers game on today's card.

In short

This page carries every graded pick on Bills vs Panthers this season and updates the next time they meet. No graded picks on Bills vs Panthers yet this season.

Form and injuries

Bills
2026 season

Record

6-1

No. 1 in the AFC East

Streak

W3

Home and away

Home 3-1 · Away 3-0

points per game

Scored33.3
Allowed25.9

Injuries

  • Daequan Hardy (CB) — Injured Reserve · Undisclosed
  • Darrick Forrest (S) — Injured Reserve · Undisclosed
  • Dorian Strong (CB) — NFI · NFI-R for Week 8 vs. Baltimore
  • Jordan Hancock (CB) — Injured Reserve · Hamstring
  • Tyrell Shavers (WR) — PUP · Knee
  • Zane Durant (DT) — Injured Reserve · Undisclosed
  • +7 more
Panthers
2026 season

Record

3-4

No. 1 in the NFC South

Streak

L2

Home and away

Home 1-2 · Away 2-2

points per game

Scored25.4
Allowed27.6

Injuries

  • AJ Dillon (RB) — Sidelined · Coach's Decision
  • Akayleb Evans (CB) — Injured Reserve · Triceps
  • Bobby Brown III (DT) — active · Hand
  • Brady Christensen (G) — Injured Reserve · Hamstring
  • Cam'Ron Jackson (DT) — Injured Reserve · Shoulder
  • Damien Lewis (G) — active · Knee
  • +11 more

The model's NFL record

57

graded picks

57

decided

45.6%

win rate

-8.5

net units

-12.3%

ROI

MarketDecidedWin %NetROI
Moneyline5745.6%-8.5-12.3%

Meetings this season

No graded picks on Bills vs Panthers yet this season.

Keep reading

Both teams, the league, and how the numbers are kept.