49ers vs Rams prediction

No 49ers vs Rams game on today's card.

In short

This page carries every graded pick on 49ers vs Rams this season and updates the next time they meet. No graded picks on 49ers vs Rams yet this season.

Form and injuries

49ers
2026 season

Record

6-1

No. 1 in the NFC West

Streak

L1

Home and away

Home 4-0 · Away 2-1

points per game

Scored28.1
Allowed19.9

Injuries

  • Alfred Collins (DT) — Injured Reserve · Knee
  • Demarcus Robinson (WR) — Injured Reserve · Ankle
  • Isaac Guerendo (RB) — PUP · Pectoral
  • Jake Tonges (TE) — Injured Reserve · Knee - MCL
  • Kalia Davis (DT) — Injured Reserve · Quadriceps
  • Nickolas Martin (LB) — Injured Reserve · Hamstring
  • +10 more
Rams
2026 season

Record

4-4

No. 3 in the NFC West

Streak

W2

Home and away

Home 2-3 · Away 2-1

points per game

Scored24.3
Allowed21

Injuries

  • Blake Grupe (PK) — Injured Reserve · Knee - ACL
  • Daniel Rickert (DE) — Injured Reserve · Knee
  • Davante Adams (WR) — Injured Reserve · Hamstring
  • Kobie Turner (DE) — Injured Reserve · Groin
  • Matthew Caldwell (QB) — Injured Reserve · Undisclosed
  • Poona Ford (DT) — Injured Reserve · Triceps
  • +7 more

The model's NFL record

57

graded picks

57

decided

45.6%

win rate

-8.5

net units

-12.3%

ROI

MarketDecidedWin %NetROI
Moneyline5745.6%-8.5-12.3%

Meetings this season

No graded picks on 49ers vs Rams yet this season.

Keep reading

Both teams, the league, and how the numbers are kept.