49ers vs Falcons prediction

No 49ers vs Falcons game on today's card.

In short

This page carries every graded pick on 49ers vs Falcons this season and updates the next time they meet. Across 1 meeting this season, PicksToday.AI has graded 1 pick on 49ers vs Falcons, for -1.0 net units.

Form and injuries

49ers
2026 season

Record

6-1

No. 1 in the NFC West

Streak

L1

Home and away

Home 4-0 · Away 2-1

points per game

Scored28.1
Allowed19.9

Injuries

  • Alfred Collins (DT) — Injured Reserve · Knee
  • Demarcus Robinson (WR) — Injured Reserve · Ankle
  • Isaac Guerendo (RB) — PUP · Pectoral
  • Jake Tonges (TE) — Injured Reserve · Knee - MCL
  • Kalia Davis (DT) — Injured Reserve · Quadriceps
  • Nickolas Martin (LB) — Injured Reserve · Hamstring
  • +10 more
Falcons
2026 season

Record

3-5

No. 3 in the NFC South

Streak

L1

Home and away

Home 1-3 · Away 2-2

points per game

Scored21.4
Allowed23.6

Injuries

  • Beaux Collins (WR) — Injured Reserve · Hip
  • Billy Bowman (CB) — Sidelined · Hamstring
  • Brian Robinson Jr. (RB) — Sidelined · Hamstring
  • DeAngelo Malone (LB) — PUP · Undisclosed
  • Divine Deablo (LB) — Sidelined · Forearm
  • Jalon Walker (LB) — Injured Reserve · Knee - ACL
  • +9 more

The model's NFL record

57

graded picks

57

decided

45.6%

win rate

-8.5

net units

-12.3%

ROI

MarketDecidedWin %NetROI
Moneyline5745.6%-8.5-12.3%

Meetings this season

MarketPickPriceResultUnits
October 25, 2026
MoneylineSan Francisco 49ers ML-143LOSS-1u

Keep reading

Both teams, the league, and how the numbers are kept.