49ers vs Commanders prediction
No 49ers vs Commanders game on today's card.
In short
This page carries every graded pick on 49ers vs Commanders this season and updates the next time they meet. Across 1 meeting this season, PicksToday.AI has graded 1 pick on 49ers vs Commanders, for +0.2 net units.
Form and injuries
49ers
2026 season
Record
6-1
No. 1 in the NFC West
Streak
L1
Home and away
Home 4-0 · Away 2-1
points per game
Scored28.1
Allowed19.9
Injuries
- Alfred Collins (DT) — Injured Reserve · Knee
- Demarcus Robinson (WR) — Injured Reserve · Ankle
- Isaac Guerendo (RB) — PUP · Pectoral
- Jake Tonges (TE) — Injured Reserve · Knee - MCL
- Kalia Davis (DT) — Injured Reserve · Quadriceps
- Nickolas Martin (LB) — Injured Reserve · Hamstring
- +10 more
Commanders
2026 season
Record
2-4
No. 3 in the NFC East
Streak
W1
Home and away
Home 2-1-1 · Away 0-3
points per game
Scored22.7
Allowed26
Injuries
- Daron Payne (DT) — Sidelined · Foot
- Jacory Merritt (RB) — Injured Reserve · Groin
- Javon Kinlaw (DT) — Sidelined · Knee
- Javontae JeanBaptiste (LB) — Injured Reserve · Pectoral
- Jaylin Lane (WR) — Injured Reserve · Ankle
- Leo Chenal (LB) — Injured Reserve · Neck
- +6 more
The model's NFL record
57
graded picks
57
decided
45.6%
win rate
-8.5
net units
-12.3%
ROI
| Market | Decided | Win % | Net | ROI |
|---|---|---|---|---|
| Moneyline | 57 | 45.6% | -8.5 | -12.3% |
Meetings this season
| Market | Pick | Price | Result | Units |
|---|---|---|---|---|
| October 19, 2026 | ||||
| Moneyline | San Francisco 49ers ML | -435 | WIN | 0.23u |
Keep reading
Both teams, the league, and how the numbers are kept.